Themis R. Kyriakides

Professor of Biomedical Engineering

Phone:
(203) 737-2214

Room / Office:
Amistad 301C

Office Address:

10 Amistad Street
New Haven, CT 06519

Mailing Address:

P.O. Box 208089
New Haven, CT 06520

Website: Kyriakides Lab

Cellular and molecular events at the interface between implanted biomaterials and tissues;
Biomaterial-induced inflammation, wound healing, tissue regeneration with a focus on angiogenesis, and extracellular matrix remodeling;
In vivo work on genetically-modified mice; gene delivery from biomaterials;
Development of biodegradable polymers;
Modification of glucose sensors;
Development of artificial skin

Moore LB, Sawyer AJ, Saucier-Sawyer J, Saltzman WM, Kyriakides TR. Nanoparticle delivery of miR-223 to attenuate macrophage fusion. Biomaterials (2016 in press).
Bancroft T, Bouaouina M, Roberts S, Lee M, Calderwood DA, Schwartz M, Simons M, Sessa WC, Kyriakides TR. Upregulation of Thrombospondin-2 in Akt1-null Mice Contributes to Compromised Tissue Repair due to Abnormalities in Fibroblast Function. J Biol Chem. pii: jbc.M114.618421. 2014.
Sawyer AJ, Tian W, Saucier-Sawyer JK, Rizk PJ, Saltzman WM, Bellamkonda RV, Kyriakides TR. The effect of inflammatory cell-derived MCP-1 loss on neuronal survival during chronic neuroinflammation. Biomaterials. 35:6698-706. 2014.
Padmanabhan J, Kinser ER, Stalter MA, Duncan-Lewis C, Balestrini JL, Sawyer AJ, Schroers J, Kyriakides TR. Engineering cellular responses using nanopatterned bulk metallic glass. ACS Nano 8:4366-75. PMID: 24724817. 2014.